When most people hear “migraine genetics,” they tune out, after all, you don’t need a DNA test to tell you that you get migraine headaches. But research drawn from genome-wide association studies is revealing something far more useful: the specific biological systems that misfire in the migraine brain, and why some people suffer so much more than others.
One fascinating example is the methylation pathway, your body’s internal recycling program. Genes in this pathway convert a compound called homocysteine into methyl groups that support nearly every process in the body. When the system runs poorly, homocysteine builds up, and elevated homocysteine has been linked to worse migraine, particularly migraine with aura, as well as increased cardiovascular risk.
SMALL HABITS THAT SUPPORT THIS PATHWAY
● Folate-rich leafy greens ● The methylcobalamin form of B12 ● Eggs, fish, dairy & meat ● Asking about homocysteine testing ● Tracking patterns in a headache diary
These habits gently support the biology underneath migraine headaches, but for most people with frequent migraine, tweaking one pathway is rarely enough on its own.
To book a consultation, call Nabeta Dentistry at (905) 639-6701 or request an appointment online at NabetaDentistry.com/appointment-request. Dr. Jared Nabeta, General Dentist, assesses jaw pain and TMD, including headache related to TMD. Treatment for migraine is offered only for migraine diagnosed by a physician, in coordination with the patient’s physician.